The mitochondria in human cells are the cell’s power plant. Coenzyme I in the mitochondria is important for metabolism of aerobic oxidizing tricarboxylic acid to ATP molecule. It acts as a hydrogen ion receptor and transfers hydrogen ions to oxygen, so that the body can obtain The three major types of nutrients, sugar, fat and protein, are converted into energy and other metabolic activities required by the human body through the TCA cycle.
Coenzyme I (NAD+) is consumed as a substrate to generate gene-repairing enzyme PARP1, it restores activity of PARP1 bounded and inactivated by protein DBC1, and repair genes by recoding damaged genes according to normal gene sequence.
Coenzyme I (NAD+) sustains the inetercellar communication between nucleus and mitochondria. The miscommunication will cause mitochondria dysfunction, known as one of the hallmarks of aging of cells. In addition, Coenzyme I is consumed as the only substrate to produce histone deacetylation enzymes Sirtuins. Sirtuins are anti-aging proteins, which can eliminate the increasing epigenetic noise during cell metabolism, sustain expression of mitochondrially encoded genes, maintain function of cells, and slow down cell aging process.
During exercise, muscle cells release growth factors that later received by capillary epidermal cells to accelerate muscle growth. The whole process relies on Sirtuin 1 the DNA-repairing protein generated by coenzyme I. In the aging process of human life, with the decline of coenzyme I, the less effective the exercise stimulates muscle growth.
Alcohol metabolism consists of two steps. First, it is converted to toxic acetaldehyde, and then degraded to harmless acetic acid. Both steps need the catalysis of Coenzyme I.
HONG KONG ABA CHEMICALS CORPORATION LIMITED is established in Hongkong in 2017. As the subsidiary of ABA chemicals corporation, HONG KONG ABA CHEMICALS CORPORATION LIMITED is dedicated to the sales of monomer & compound preparation of NMN. ABA Chemicals corporation, where our R&D center located, supplies NMN raw material with advanced manufacturing technics;The trademark - Wholly You is the valuable brand and asset of our own.
Abinopharm, Inc. is located in New Haven, Connecticut, USA and focuses on the R&D, regulatory filing, and
commercialization of biopharmaceutical products (including dietary supplements) in the USA.
NMN is one of our major dietary supplements developed on the base of sound scientific researches. It is manufactured under strict US FDA cGMP by our award winning partner who is one of the best dietary supplement manufacturers in the US.